Suci Rahayu Evasha., Working at RSUD Raden Mattaher Jambi. Follow. Published on Oct 8, 0 Comments; 0 Likes; Statistics; Notes. Full Name. Comment. Nagtegaal I D, de Velde C J van, Marijnen C A, Krieken J H van, Quirke P. Low rectal cancer: a call for a change of approach in abdominoperineal resection. Nagtegaal ID, van de Velde CJ, Marijnen CA, van Krieken JH, Quirke P, Dutch Colorectal Cancer G. et al. Low rectal cancer: a call for a change.

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Involvement of the mesorectal fascia, which is the CRM during the surgical resection, is an important prognostic factor highly predictive of residual tumor and local recurrence.

Cancer Antigens (CEA and CA ) as Markers of Advanced Stage of Colorectal Carcinoma

Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: Recurrences are treated by salvage abdominoperineal resection. At this point, the abdominal portion is completed and attention is turned to the perineal dissection, which is undertaken as described above.

Using a finger on the tip of the coccyx as a guide, cca posterior dissection is directed anterior to the coccyx and the anococcygeal raphe is divided. Cancer was twice more common in men than in women.

Transanal excision vs major surgery for T1 rectal cancer.

Abdominoperineal Resection: How Is It Done and What Are the Results?

In the case of CA the highest average values were observed in case of liver metastases Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. Due to the ability of MRI to detect intranodal signals and irregularity of their borders, MRI has a higher sensitivity than EUS for the assessment of perirectal nodal involvement 63 – Combined modality therapy including intraoperative electron irradiation for locally recurrent colorectal cancer.


There are no strong data on the use of adjuvant chemotherapy for these patients. Age and gender are important risk factors affecting both colon and rectal cancers 2.

Is stoma relocation superior to fascial repair. Preoperative preparation and patient positioning are identical to the open procedure, although a lesser degree of hip flexion may be necessary to allow uninhibited dissection in the left colic gutter.

An overview on anatomy, epidemiology and risk factors will be discussed first and then we will go through clinical presentations, current staging and screening protocols and latest approaches on diagnosis and treatment modalities of rectal cancer. In the case of CA the highest average values were observed in the localization at sigma Metastases were observed in 37 patients, with predominance in the liver 22 adalan and both liver and lungs 5 cases.

CT or high-resolution MRI?

TRUS is an accurate modality for locoregional staging of rectal cancers using its ability to distinguish tumors involving the mucosa and submucosa from those involved the muscularispropria or perirectal fat Not only it has an established role in initial staging of the tumor, but also it can be utilized for evaluation of treatment response and local recurrence 5. However, there is no clear evidence available on the best approach; initial resection of the primary tumor or initial systemic therapy Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Favorable clinical response to preoperative chemoradiation and tumor downstaging predict better 5-year survival and local control rates.


An interesting study by Zolciak and colleagues 35 looked at patient preferences before and after rectal cancer resection. These regimen include bolus or infusionalfluorouracilthe Roswell Park regimen weekly bolus fluorouracil plus leucovorinthe de Gramont regimen short-term infusionalfluorouracil and leucovorin ,capecitabine an orally active fluoropyrimidines or oxaliplatin-based regimen such as FOLFOX infusionalfluorouracil and leucovorin plus oxaliplatin or CAPOX Capecitabine plus oxaliplatin regimen.

Comparative study of transrectal ultrasonography, pelvic computerized tomography, and magnetic resonance imaging in preoperative staging of rectal cancer.

A pad is placed under the sacrum to protect it as well as to allow the perineum to project beyond the end of the table. The fascia and skin are closed and the colostomy is matured at skin level with multiple interrupted, absorbable sutures and full-thickness through the bowel through the dermis.

Analysis of the average value of CEA shows that it was higher in males Randomized clinical trial comparing laparoscopic and open surgery in patients with rectal cancer.

Rectal cancer is the second most common cancer in large intestine. These regimens include infusional or bolus fluorouracil aloneand leucovorin plus fluorouracil Prevalence of K-ras mutations and mutation patterns in the p53 gene in avalah cancers are also different zdalah those seen in colon cancers 9.

What we found by exploring the colon cancer is that they were extremely higher CEA and CA values in patients who have had cancer in the right hemicolon.